【佳学基因检测】肿瘤学中寡核苷酸治疗的贼新进展
肿瘤基因检测十大公司排序
阅读肿瘤基因解码协会如何提升基因检测的正确性知悉《PLoS One》在 2021; 16(2): e0247090发表了一篇题目为《肿瘤学中寡核苷酸治疗的贼新进展》肿瘤靶向药物治疗基因检测临床研究文章。该研究由Sadaaki Nishimura, Conceptualization, Data curation, Investigation, Software, Visualization, Writing – original draft, Atsushi Sugimoto, Data curation, Shuhei Kushiyama, Data curation, Shingo Togano, Data curation, Investigation, Kenji Kuroda, Data curation, Resources, Yurie Yamamoto, Data curation, Makoto Yamauchi, Data curation, Resources,‡ Toshiyuki Sumi, Data curation, Resources,‡ Hiroyasu Kaneda, Data curation, Resources,‡ Tomoya Kawaguchi, Data curation, Investigation,‡ Minoru Kato, Data curation, Formal analysis, Investigation,‡ Mizuki Tagami, Data curation, Formal analysis,‡ Naoto Oebisu, Data curation, Project administration,‡ Manabu Hoshi, Data curation, Investigation,‡ Kenjiro Kimura, Data curation, Investigation,‡ Shoji Kubo, Data curation, Investigation,‡ Kazuya Muguruma, Data curation, Formal analysis,‡ Tsutomu Takashima, Data curation, Formal analysis,‡ Masaichi Ohira, Data curation, Investigation, and Masakazu Yashiro, Project administration, Resources, Supervision, Writing – review & editing,等完成。促进了肿瘤的正确治疗与个性化用药的发展,进一步强调了基因信息检测与分析的重要性。
肿瘤靶向药物及正确治疗临床研究内容关键词:
反义寡核苷酸,siRNA,适体,DNA核酶,癌症
肿瘤靶向治疗基因检测临床应用结果
癌症是全球主要的死亡原因之一。在过去的几十年里,包括手术、放射和化学疗法在内的传统疗法已经提高了许多类型癌症的存活率。然而,癌症反复和/或转移到远处器官仍然是主要挑战,导致大量未满足的临床需求。寡核苷酸疗法,包括反义寡核苷酸、小干扰 RNA 和适体,在杜氏肌营养不良症、家族性淀粉样神经病和黄斑变性等疾病适应症方面显示出有希望的临床结果。虽然目前还没有批准用于任何类型癌症的寡核苷酸药物,但在临床前研究和临床试验中获得的结果令人鼓舞。在这里,我们概述了肿瘤学中寡核苷酸治疗领域的贼新进展,回顾了当前的临床试验,并讨论了相关挑战。关键词:反义寡核苷酸、siRNA、适体、脱氧核糖核酸酶、癌症
肿瘤发生与反复转移国际数据库描述:
antisense oligonucleotides, siRNA, aptamers, DNAzymes, cancers
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